Factory FLOW is an integrated material handling system in a visual environment. It enables engineers to analyze factory layouts by using part routing information, material storage needs, material handling equipment specifications, and part packaging (containerization) information. Factory Flow is used for optimizing layouts based on material flow distances, frequency, and costs.
Factory FLOW product pdf, 1430kb 
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Above: Material Flow analysis on 2D AutoCAD layout

Above: Factory Flow Editor GUI enable users to define Assembly Data